How do thoughts interact with the physical universe? Our movements and actions seem to be simple responses to the signals from our brain, but what triggers those neurons? I mean, we –chose - to act. We think “do I want to do this, yes.” Then do it. How is that possible? If it’s possible for immaterial things like thoughts with no apparent location in the physical universe to interact with our neurons then why isn’t it possible for imaginary concepts to interact with other physical catalysts?